Original Research Paper
Histopathological Evaluation of Endometrium in AUB Cases
Background: Abnormal uterine bleeding (AUB) is defined as any bleeding that does not correspond with the frequency, duration or amount of blood flow of a normal menstrual cycle. It is a common reason for women of all ages to visit gynaecologist resulting in unrequired hysterectomy in developing countries. The aim of the present study was to determine the clinical spectrum and pathologies of endometrium by endometrial biopsy of patients with AUB in study population.Methods: This prospective study was carried out from September 2018 June 2020 in the Department of Obstetrics & Gynaecology, at Shri Mahant Indiresh Hospital, Dehradun. It was done on women presenting with abnormal uterine bleeding. This study was a prospective study done on 124 patients presenting with AUB who underwent endometrial biopsy. The histopathological patterns of endometrium studied and data analysed. Results: The commonest presenting complaint in AUB patients was heavy menstrual bleeding seen in 81(65.3%) followed by irregular menstrual bleeding in 25(20.2%) cases. The predominant endometrial histopathological finding was secretory endometrium 39cases (31.45%), proliferative endometrium in 25cases (20.16%) and simple hyperplasia without atypia 29 cases (23.38%). Malignant lesions were more common in patients more than 50yrs of age and comprised of 2 cases (1.61%) of all cases. Conclusion: Histopathological examination of the endometrium showed a wide spectrum of pathological changes from normal endometrium to malignancy. It is important to confirm the underlying disorder in all cases of AUB evaluation especially in peri- and post-menopausal women. Accurate analysis of endometrial sampling is the key to choose ideal treatment modality for obtaining desired optimal outcome.
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