Research Paper

Fetomaternal outcome of severe anemia in pregnancy with special reference to macrocytic anemia

  Abstract :

Anemia in pregnancy has been synonymous with iron-deficiency anemia but there appears to be a changing trend with emerging evidence of macrocytic anemia. The aim of this study was to evaluate the clinical profile of patients having severe anemia in pregnancy and its fetomaternal outcome with special reference to macrocytic anemia.Our study was prospective cohort study which included all antenatal patients presenting with severe anemia (hemoglobin 7 gm%) over a period of 1 year from July 2014 to June 2015 in the Department of OBG, KGMU, Lucknow, India.On comparing the results it was found that maternal and fetal morbidity and mortality is higher in subjects with macrocytic anemia as compared to iron-deficiency anemia. Hence all pregnant women with severe anemia should be investigated for serum Vitamin B12, which can help in early diagnosis and prevention of progression of severe anemia and optimizing both maternal and perinatal outcomes.

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