Original Research Paper

Relationship Between Bilirubin Levels And Carotid Intima-Media Thickness In Polycystic Ovary Syndrome Patients

  Abstract :

To evaluate the plasma bilurubin levels and carotid intima-media thickness (CIMT) in patients with polycystic ovary syndrome (PCOS).Thirty seven patients with a diagnosis of PCOS aged younger than 40 year and thirty six healthy women were included in the study. Serum bilirubin levels and other blood parameters in at least 12-hour fasting states were determined. Carotid artery ultrasonography imaging was performed by the same experienced operator. Average of left and right carotid arteries was taken as one variable.Serum bilurubin levels were significantly lower ( p: 0,02 )in PCOS patients. In addition, IMT in this group was significantly higher. CIMT showed a significant positive correlation with LDL levels and a significant negative correlation with bilirubin levels in both the groups.To the best of our knowledge, this is the first study to evaluate serum bilirubin levels in patients with PCOS. We found that serum bilirubin levels were independently associated with CIMT. Therefore, adverse effects of oxidative stress were shown on vessel structure

  Cite This Article:

  References:

  Article: