To Investigate the Association between Triple test and Pre-term delivery.
Sehat. Z, Goshetasbi. A, Tahery Amin. M
Background: Preterm labor is one of the main problems of health care and one of the main factors in neonatal mortality and morbidity. It's important that with efforts to predict and prevent premature delivery that can cause infant deaths. Objective: To investigate the association between Triple test (HCG, MSAFP and UE3) and Pre-term delivery.Methods: This is a historical Cohort Study that has been performed for 700 pregnant women, clients of Nilou Lab in the second trimester of pregnancy to take the Triple test between March and September 2012. The information of Mothers having required conditions to enter to the study has been registered and after delivery, they called again to be interviewed. These data sets using statistical tests: chi-square test and ROC Curve was analysis.Results: There is a direct relationship between the increase AFP (P value =0.011) serum level and preterm delivery. Also, there is an inverse relationship between the UE3 (P value =0.002) serum level and preterm delivery. Moreover, there is not any relationship between the increase HCG (P value =0.68) serum level and preterm delivery.Conclusion: The increase in the AFP and decrease in UE3 serum levels in the second trimester of pregnancy lead to enhance the probability of preterm delivery. Moreover, if the current study is done with higher samples and different sampling environment, may be having different results.
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