Original Research Paper

To estimate the sensitivity and negative predictive value of rapid antigen test in comparison NAATs for diagnosis of Covid-19 infection in pregnant women.

Dr Suparna Grover, Dr Sujata Sharma

  Abstract :

INTRODUCTION: This unprecedented pandemic has proved to be a challenge to treat and early detection and isolation has been an important management strategy. Various tests available are the bedside rapid antigen test and the more complex nucleic acid amplification tests.MATERIAL AND METHODS: The study was done on all obstetric patients admitted under the department of Obstetrics and Gynaecology, Government Medical College, Amritsar from 14/8/2020 to 30/11/2020. These patients were tested with Rapid antigen test (RAT) as a screening test for COVID infection, irrespective of the symptoms. All the patients who tested negative with rapid antigen test were subjected to one of the confirmatory nucleic acid amplification tests (NAAT) like RT-PCR or TrueNat. The study excluded all the patients who were known Covid-19 positive at the time of admission.RESULTS: 1574 patients were included in the study. Sensitivity and negative predictive value of the rapid antigen test was 27.9% and 94.8% and that of TrueNat and RT-PCR were 90.9%; 99.09% and 72.34%; 98.86% respectively.CONCLUSION: In times of high prevalence, Rapid antigen test (RAT) continue to be relevant in spite of disappointing sensitivity due to their role in decreasing the risk of transmission in hospital setting but continued research needed to develop better bedside tests with higher sensitivity.


  Cite This Article:

TO ESTIMATE THE SENSITIVITY AND NEGATIVE PREDICTIVE VALUE OF RAPID ANTIGEN TEST IN COMPARISON NAATS FOR DIAGNOSIS OF COVID-19 INFECTION IN PREGNANT WOMEN., Dr Suparna Grover, Dr Sujata Sharma, INTERNATIONAL JOURNAL OF ADVANCES IN GYNAECOLOGY : Volume-6 | Issue-1 | March-2022

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